AOD-9604

AOD-9604 (Anti-Obesity Drug-9604) is a synthetic peptide fragment of human growth hormone (HGH), consisting of amino acids 176–191. Unlike full HGH, AOD-9604 does not stimulate IGF-1 production or general growth pathways. Instead, it has been studied primarily for its potential role in regulating fat metabolism. It remains experimental and is not FDA-approved as a therapy.

How It Is Used in Research Settings

• Explored for stimulating lipolysis (fat breakdown) and inhibiting lipogenesis (fat storage) in adipose tissue models.
• Studied in obesity and metabolic syndrome research for weight management support.
• Examined in animal studies for potential effects on cartilage repair and joint health.
• Investigated as a safer alternative to HGH without impacting blood sugar or IGF-1 pathways.

Proposed Uses (Research Areas)

• Obesity and fat metabolism studies.
• Metabolic syndrome and insulin resistance models.
• Joint repair and cartilage protection (preclinical data).
• Aging and weight management research.

How It Is Dosed in Research Settings

• Injectable: Typically studied at 300 mcg to 600 mcg subcutaneously once daily.
• Oral formulations: Investigated in capsule form, though bioavailability and efficacy are less well established.
• Cycle length: Common research protocols range from 12–24 weeks for weight and metabolic outcomes.
• Handling: Supplied as a lyophilized powder; reconstituted with bacteriostatic water and stored refrigerated.

Important Considerations

• Regulatory status: AOD-9604 is not FDA-approved; all applications remain experimental.
• Evidence base: Most data comes from preclinical studies and small clinical trials; larger studies are needed.
• Safety: Reported as well tolerated in short studies, with low risk of hypoglycemia compared to HGH. Long-term safety is unknown.

Disclaimer

This material is provided for educational purposes only and summarizes published research on AOD-9604. It is not medical advice. AOD-9604 is experimental, not FDA-approved, and should not be viewed as a therapy for medical use.

This peptide is for research use only.